Here's a complete list of what I had to do in order to run a second facilitator instance on the same host where one instance was already running. I only set up facilitator, facilitator.cgi, and facilitator-reg-daemon, not the email poller. I ran facilitator on port 10002 and facilitator-reg-daemon on 10003.
Change the port number in FACILITATOR_ADDR to 10002 in facilitator-reg-daemon (this is what is noted in the ticket description).
Change the port number in FACILITATOR_ADDR to 10002 in facilitator.cgi.
Change the path to facilitator-reg in the Popen call in fac.py, and add the extra arguments -p 10003.
Setting the port numbers of facilitator and facilitator-reg-daemon, I was able to do through those programs' -p options.